O what extent is clozapine effective in the treatment and management Dissertation

O what extent is clozapine effective in the treatment and management of resistant schizophrenia - Dissertation Example Based on the inclusion and exclusion criteria, only 10 studies were included in the actual synthesis of data. Result: With regards to treating patients with either treatment-resistant schizophrenia or those who are partially responsive to clozapine monotherapy, only 7 out of 10 studies that were officially included in this review of literature focused on examining the effectiveness of clozapine therapy when combined with another antipsychotic drugs (i.e. amisulpride, aripiprazole, risperidone, and quetiapine). The other 3 remaining studies are all equally useful in the completion of the literature review particularly with regards to the basic information on clozapine, treatment-resistant schizophrenia, and the drug potency of clozapine versus other types of antipsychotic drugs such as amisulpride, olanzapine, quetiapine, risperidone, or ziprasidone. Conclusion: Combining the usual dose of clozapine with another antipsychotic drug such as aripiprazole, amisulpride, or quetiapine are a ll equally effective in terms of treating patients with either treatment-resistant schizophrenia or those patients with partial response to certain antipsychotic drug. Unlike the process of combining the use of clozapine therapy with aripiprazole, amisulpride, or quetiapine, combining the use of clozapine therapy with risperidone remains uncertain. Acknowledgements I would like to thank my parents for extending their emotional support to me throughout the completion of my dissertation paper. To my supervisor _____________ (insert name) who has guided me all the way throughout the progress of each chapter of my research study. Table of Contents Abstract ................................................................................................................................ 2 Acknowledgements .............................................................................................................. 4 Table of Contents ......................................................... ........................................................ 5 1.0 Introduction and Background ................................................................................... 7 1.1 Nature and Purpose of the Dissertation ..................................................... 8 1.2 Relevance of the Discussion to the Role and Responsibilities of Nurses and the Clients ............................................................................... 8 1.3 Relationship of the Subject to Current National and Healthcare / Social Care Policy, Priority, and Agendas ................................................ 8 1.4 Historical / Contemporary or Other Contextual Issues which Impacts the Subject ................................................................................... 9 1.5 Aims and Purpose of the Research Study .................